Novel diagnostics and treatment of endometriosis based on protein glycosylation and its association with microbes


Research Area:


What is the research about?

Endometriosis is a painful disease affecting women of reproductive age. It is characterized by a tissue, which should be in the uterus, growing outside the uterus. This causes pain, mainly during periods when this tissue should be shed by menstrual blood and leads to internal bleeding. Women with endometriosis can have difficulties in conceiving and/or carrying a pregnancy. The exact cause of this disease is not known. It is often diagnosed late when it has already progressed. Only laparoscopy offers an exact diagnosis. Better, non-invasive diagnosis is needed. Treatment is directed at the symptoms and only works partially or not at all. If we understood the disease better, we could provide significant improvements in treatment and diagnosis and patients would not suffer most of their lives, with pain and fertility problems. We propose to look at the sugars in blood, uterine fluid and tissues taken from endometriosis patients. We will also monitor for hormones, which are known to be dysregulated in endometriosis. Bacterial infection can also occur in women with endometriosis and we aim to investigate if the sugars present on diseased tissue play a role in enabling bacteria to attach to the tissue and establish infection. Sugars that occur in tissue, blood or uterine fluid of patients could be used for diagnosis of disease and identification of sugars that play a role in mediating infection would allow us to develop therapies to block infection and treat disease.

Opportunity for:

Person living with condition

Involvement Opportunity Details


Time commitment:

During grant writing, up to 2x1 hour meetings online. If funded, we will have up to 4 x 1 hour meetings per year for 2 years

Contact between meetings:


Length of involvement:

1 month initially, if funded 2 years

Start date for involvement:




Online / In Person

If online, explain how:


If in person, explain where:

National Institute for Bioprocessing Research and Training (NIBRT), Foster Avenue, Mount Merrion, Blackrock, Co. Dublin, A94 X099

Other ways of communicating:


Funding available for:

PPI contributor’s time

If no funding available, explain why:

Not applicable

Other Information

Stage of the research study/ programme:

Early planning

Is this opportunity for PPI in a PhD:


Closing date to contact researchers:


Research Team

Contact person:

Radka Fahey (Saldova)



Contact email:

Researcher background:


Research funder:



Interested in this PPI Opportunity?

Please complete this form and click SUBMIT

Scroll to Top